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Transvection Goes Live—Visualizing Enhancer-Promoter Communication between Chromosomes
Albert Tsai, Robert H. Singer, Justin Crocker Molecular Cell Volume 70, Issue 2, Pages (April 2018) DOI: /j.molcel Copyright © 2018 Elsevier Inc. Terms and Conditions
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Figure 1 Models of Transvection
The left panel illustrates the classic genetics model of transvection, whereby the enhancer interacts directly with the promoter in trans to drive transcription. The right panel shows transcriptional hubs formed through cooperative interactions between insulators, enhancers, promoters, and transcription factors. Such hubs contain a common pool of transcription factors that can be shared between enhancers and promoters without direct competition. Molecular Cell , DOI: ( /j.molcel ) Copyright © 2018 Elsevier Inc. Terms and Conditions
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