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Fulminant Hepatic Failure Secondary to Erlotinib
Weitian Liu, Frederick L. Makrauer, Amir A. Qamar, Pasi A. Jänne, Robert D. Odze Clinical Gastroenterology and Hepatology Volume 5, Issue 8, Pages (August 2007) DOI: /j.cgh Copyright © 2007 AGA Institute Terms and Conditions
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Figure 1 Medium-power photograph of the liver showing severe active hepatitis with marked portal inflammation, consisting of lymphocytes, plasma cells, and neutrophils. The portal tracts also show bile ductular proliferation, piecemeal necrosis, and hepatocyte loss in the periportal and lobular region. In other areas, there was severe bridging necrosis. These findings are most consistent with drug toxicity. Clinical Gastroenterology and Hepatology 2007 5, DOI: ( /j.cgh ) Copyright © 2007 AGA Institute Terms and Conditions
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