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Intensified ovarian stimulation in a GnRH antagonist protocol with agonist triggering: a prospective, clinical feasibility study  Georg Griesinger, Henriette.

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Presentation on theme: "Intensified ovarian stimulation in a GnRH antagonist protocol with agonist triggering: a prospective, clinical feasibility study  Georg Griesinger, Henriette."— Presentation transcript:

1 Intensified ovarian stimulation in a GnRH antagonist protocol with agonist triggering: a prospective, clinical feasibility study  Georg Griesinger, Henriette Berndt, Laura Schultz, Askan Schultze-Mosgau, Klaus Diedrich, Sören von Otte  Reproductive BioMedicine Online  Volume 22, Issue 2, Pages (February 2011) DOI: /j.rbmo Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

2 Figure 1 Schematic representation of the study protocol. ET=embryo transfer; GnRH=gonadotrophin-releasing hormone; HCG=human chorionic gonadotrophin; MPA=medroxyprogesterone acetate; OHSS=ovarian hyperstimulation syndrome; 2PN=2 pronuclear. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

3 Figure 2 Regression analysis of the relationship between the number of oocytes retrieved and number of fertilized oocytes available for cryopreservation. Line represents quadratic model of the regression equation. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

4 Figure 3 Box plots of the assessment of physical wellbeing on day 3 or 4 after oocyte retrieval by a visual analogue scale. Assessment based on 26 returned questionnaires. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

5 Figure 4 (A) Cumulative incidence of a positive human chorionic gonadotrophin test resulting in a live-born baby. (B) Cumulative incidence of live birth according to vitrified–warmed embryo transfer cycle rank. Dashed lines=intention-to-treat excluding spontaneous pregnancies (n=30); solid lines=patients undergoing at least one vitrified–warmed embryo transfer cycle (n=26). Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions


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