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Fei Sun, M. D. , Ph. D. , Paul Turek, M. D. , Calvin Greene, M. D

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Presentation on theme: "Fei Sun, M. D. , Ph. D. , Paul Turek, M. D. , Calvin Greene, M. D"— Presentation transcript:

1 Abnormal progression through meiosis in men with nonobstructive azoospermia 
Fei Sun, M.D., Ph.D., Paul Turek, M.D., Calvin Greene, M.D., Evelyn Ko, B.Sc., Alfred Rademaker, Ph.D., Renée H. Martin, Ph.D.  Fertility and Sterility  Volume 87, Issue 3, Pages (March 2007) DOI: /j.fertnstert Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

2 FIGURE 1 Human pachytene spermatocyte with synaptonemal complexes shown in red, centromeres in blue, and MLH1 foci in yellow. For the cells in this stage, all 23 homologues (red) are synapsed and MLH1 foci are evident. Two synaptonemal complexes have splits (sp), and another synaptonemal complex has a gap (g); sex chromosomes are marked. Sun. Meiotic abnormalities in infertile men. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

3 FIGURE 2 Mean number (±SD) of MLH1 foci per pachytene spermatocyte in the controls and patients with nonobstructive azoospermia (NOA). Sun. Meiotic abnormalities in infertile men. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions


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