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Fig. 10. COL15A1 is pervasive within advanced human atherosclerotic plaques and localized to the fibrous cap and intraplaque microvessels. A representative.

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Presentation on theme: "Fig. 10. COL15A1 is pervasive within advanced human atherosclerotic plaques and localized to the fibrous cap and intraplaque microvessels. A representative."— Presentation transcript:

1 Fig. 10. COL15A1 is pervasive within advanced human atherosclerotic plaques and localized to the fibrous cap and intraplaque microvessels. A representative image of a human coronary artery lesion from 1 of 6 patients analyzed who underwent coronary artery bypass surgery is shown. Serial sections were stained with COL15A1 (A) or traditional macrophage (CD68; B) and SMC marker (ACTA2) genes. C and D: boxes (1 and 2) represent regions of higher magnification to highlight COL15A1 presence in the ACTA2-rich fibrous cap (C and D) and intraplaque microvessels (D, blue arrows) with little to no COL15A1 staining in CD68-rich regions (D). DOI: ( /ajpheart )

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