Presentation is loading. Please wait.

Presentation is loading. Please wait.

Leptin-induced LTP involves a PI 3-kinase-dependent process.

Published byMervyn Allen Modified over 5 years ago

Similar presentations

Presentation on theme: "Leptin-induced LTP involves a PI 3-kinase-dependent process."— Presentation transcript:

1 Leptin-induced LTP involves a PI 3-kinase-dependent process.
Leptin-induced LTP involves a PI 3-kinase-dependent process. A, B, Plots of pooled and normalized data illustrating the effects of leptin on synaptic transmission in the presence of the PI 3-kinase inhibitor LY (10 μm; A) or the ERK inhibitor U0126 (10 μm; B), respectively. Leptin-induced LTP was prevented following blockade of PI 3-kinase, but not ERK. Calibration: 0.2 mV, 100 ms. C, Histogram of the pooled data showing the relative effects of leptin (100 nm) on synaptic transmission in control conditions and in the presence of either LY (10 μm), wortmannin (50 nm), U0126 (10 μm), or PD98059 (10 μm). Xiao Luo et al. eneuro 2015;2:ENEURO ©2015 by Society for Neuroscience

Download ppt "Leptin-induced LTP involves a PI 3-kinase-dependent process."

Similar presentations

PI 3-kinase inhibition has no effect on ANG II induced extracellular recognition kinase (ERK) 1/2 activation. PI 3-kinase inhibition has no effect on ANG.

PI 3-kinase inhibition has no effect on ANG II induced extracellular recognition kinase (ERK) 1/2 activation. PI 3-kinase inhibition has no effect on ANG.
From: Modeling Keratoconus Using Induced Pluripotent Stem Cells

From: Modeling Keratoconus Using Induced Pluripotent Stem Cells
Phosphoinositide 3-kinase inhibitors protect mouse kidney cells from cyclosporine- induced cell death  E. Sarró, O. Tornavaca, M. Plana, A. Meseguer, E.

Phosphoinositide 3-kinase inhibitors protect mouse kidney cells from cyclosporine- induced cell death  E. Sarró, O. Tornavaca, M. Plana, A. Meseguer, E.
Schematic representation of the dorsal and ventral attentional systems (DAS, VAS, outlined in blue and orange, respectively), the visual areas, and their.

Schematic representation of the dorsal and ventral attentional systems (DAS, VAS, outlined in blue and orange, respectively), the visual areas, and their.
Volume 63, Issue 2, Pages (February 2003)

Volume 63, Issue 2, Pages (February 2003)
by Xingwei Sui, Sanford B. Krantz, Min You, and Zhizhuang Zhao

by Xingwei Sui, Sanford B. Krantz, Min You, and Zhizhuang Zhao
Volume 31, Issue 5, Pages (September 2001)

Volume 31, Issue 5, Pages (September 2001)
DH E2 infusion significantly increased phosphorylation of the p42 isoform of ERK (A) and of Akt (B) in the DH of OVX females, but not sham GDX males. DH.

DH E2 infusion significantly increased phosphorylation of the p42 isoform of ERK (A) and of Akt (B) in the DH of OVX females, but not sham GDX males. DH.
The ERK phosphorylation inhibitor U0126 did not block the memory-enhancing effects of E2 in intact or GDX males. The ERK phosphorylation inhibitor U0126.

The ERK phosphorylation inhibitor U0126 did not block the memory-enhancing effects of E2 in intact or GDX males. The ERK phosphorylation inhibitor U0126.
Ganglioside GM3 Promotes Carcinoma Cell Proliferation via Urokinase Plasminogen Activator-Induced Extracellular Signal-Regulated Kinase-Independent p70S6.

Ganglioside GM3 Promotes Carcinoma Cell Proliferation via Urokinase Plasminogen Activator-Induced Extracellular Signal-Regulated Kinase-Independent p70S6.
Modeling of an isolated rhythm-generating population.

Modeling of an isolated rhythm-generating population.
A, ACPs establish direct synaptic contact with AOB GCs

A, ACPs establish direct synaptic contact with AOB GCs
PmCo feedback enhances MC responses to vomeronasal inputs.

PmCo feedback enhances MC responses to vomeronasal inputs.
Temporal Synaptic Tagging by Ih Activation and Actin

Temporal Synaptic Tagging by Ih Activation and Actin
Distribution and functionality of Arch-EGFP pumps in the peripheral sensory pathways of Nav1.8-Arch+ mice. Distribution and functionality of Arch-EGFP.

Distribution and functionality of Arch-EGFP pumps in the peripheral sensory pathways of Nav1.8-Arch+ mice. Distribution and functionality of Arch-EGFP.
Volume 39, Issue 2, Pages (July 2003)

Volume 39, Issue 2, Pages (July 2003)
Active avoidance is impaired in aged mice in both multimodal and visual versions of the task. Active avoidance is impaired in aged mice in both multimodal.

Active avoidance is impaired in aged mice in both multimodal and visual versions of the task. Active avoidance is impaired in aged mice in both multimodal.
Synaptic transmission and plasticity is disturbed in 2-week-old but not in adult SynDIG1 β-gal mutant mice. Synaptic transmission and plasticity is disturbed.

Synaptic transmission and plasticity is disturbed in 2-week-old but not in adult SynDIG1 β-gal mutant mice. Synaptic transmission and plasticity is disturbed.
NMDS clustering of sample types and differential expression analysis.

NMDS clustering of sample types and differential expression analysis.
ABLE detects synchronously spiking, densely packed cells from mouse in vitro imaging data. ABLE detects synchronously spiking, densely packed cells from.

ABLE detects synchronously spiking, densely packed cells from mouse in vitro imaging data. ABLE detects synchronously spiking, densely packed cells from.

Similar presentations

Ads by Google