1. The Nurse View

3. Introduction

4. Checkpoint Inhibition

5. Indications in GI Cancers MSI-High/dMMR Solid Tumors

6. Indications in GI Cancers MSI-H/dMMR Metastatic CRC

7. Indications in GI Cancers Advanced Gastric/GE Junction Cancers

8. Indications in GI Cancers Where Biomarkers Are Not Needed

9. Cases Where Checkpoint Inhibitors May Be Contraindicated -- or Require Close Consultation With the Oncologist

10. Microsatellite Instability

11. Genetic Testing

12. Biomarkers PD-L1

13. Biomarkers General Discussion

14. irAEs

15. irAEs Monitoring and Patient Education

16. Immunotherapy vs Chemotherapy AEs

17. Overview of Management Principles of irAEs

18. Considerations in the Management of irAEs

19. Case A 45-Year-Old Man With Colorectal Cancer

20. Patient Has Tumor That Is MSI-H

21. Educating the Patient

22. Patient Undergoes Treatment With a Checkpoint Inhibitor

23. Managing Immune-Related Hepatitis

24. Concluding Remarks

25. Abbreviations

26. Abbreviations (cont)

27. Abbreviations (cont)