1. Associations between biomarkers of subclinical inflammation and progression of DSPN assessed by changes in MNSI in individuals with DSPN in KORA F4/FF4.
Associations between biomarkers of subclinical inflammation and progression of DSPN assessed by changes in MNSI in individuals with DSPN in KORA F4/FF4. The figure shows regression coefficients (β) and corresponding 95% CIs for changes in MNSI (MNSIFF4 − MNSIF4) that are given for a doubling of circulating levels of biomarkers. Data are adjusted for age, sex, waist circumference, height, hypertension, total cholesterol, HbA1c, alcohol intake, smoking, physical activity, use of lipid-lowering drugs, use of nonsteroidal anti-inflammatory drugs, eGFR, prevalent myocardial infarction, and neurological conditions that might cause nerve damage (model 3). Solid lines indicate P < 0.05; dotted lines, P > 0.05.
Christian Herder et al. Dia Care 2017;40:
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