1. Treatment with CN-105 significantly decreased microgliosis associated with brain injury after SAH. Images of immunostained brain slices with F4/80 for microgliosis, Vehicle (A and C) and CN-105-treated (B and D), mice sacrificed 5 days post-SAH.
Treatment with CN-105 significantly decreased microgliosis associated with brain injury after SAH. Images of immunostained brain slices with F4/80 for microgliosis, Vehicle (A and C) and CN-105-treated (B and D), mice sacrificed 5 days post-SAH. Quantification by formal stereology for F4/80 positive cells (E) in the whole hippocampus in vehicle or CN-105-treated mice at 5 days after SAH (Vehicle mice 36 079±10 460; CN ±1281; p=0.036). SAH, subarachnoid haemorrhage.
Ji Liu et al. Stroke Vasc Neurol 2018;3:
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