1. Rheumatoid Arthritis F:M 2.5:1 Symmetric arthritis Inflammatory
Exam may resemble SLE
However, RA causes bony erosions, irreversible

2. Rheumatoid Arthritis Historical rx: steroids, gold 1990s: Methotrexate
1998: Biologics
Diminishing frequency of extraarticular (EA) disease features such as vasculitic ulcers

3. RA: Common Features Sjogren syndrome: Dry eyes, mouth Parotitis
May be associated with purpura, renal disease, neuropathy

4. RA: Common Features Rheumatoid nodules Extensor surfaces
Painless, do not erode
May be confused with gouty tophi

5. RA: Scleritis Nodules are not always “benign”
Nodular scleritis is painful, can be catastrophic
Aggressive po steroids

6. RA: Scleritis Painful red eye is an emergency in RA
Scleritis may cause globe rupture

7. ANCA Vasculitis (Wegener’s)

9. Wegener granulomatosis
Saddle nose deformity
Lung nodules
Hematuria, renal failure