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Table I Male Disc Participants: Mean (S.D.)

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1 Table I Male Disc Participants: Mean (S.D.)
Baseline Year 1 Year 3 N 362 342 346 Age 9.9 (0.6) 11.0 (0.6) 13.0 (0.7) SBP 99.0 (8.0) 97.8 (8.0) 101.7 (8.7) DBP 55.8 (11.0) 54.7 (10.5) 56.6 (10.3) LDL-C 129.0 (12.3) 124.3 (19.0) 118.6 (21.4) BMI 17.8 (2.5) 18.6 (3.0) 20.2 (3.4) Tanner distribution % Prepubertal 100% 49.9% 5.0%

2 Table II Female DISC Participants: Mean (S.D.)
Baseline Year 1 Year 3 N 301 285 283 Age 9.2 (0.6) 10.3 (0.6) 12.2 (0.6) SBP 95.6 (10.2) 96.2 (8.6) 98.5 (8.7) DBP 53.3 (11.7) 52.8 (11.8) 56.5 (11.2) LDL-C 132.4 (11.1) 125.5 (18.9) 115.4 (18.9) BMI 17.2 (2.2) 18.0 (2.6) 19.7 (3.3) Tanner distribution % Prepubertal 100% 42.6% 2.2%

3 Table III Physical Activity: Total MET Score Males
Baseline Year 1 Year 3 N 357 337 321 Mean (S.D.) 482.1 (49.2) 491.9 (54.1) 495.6 (56.6) 25th % ile 446.5 456.5 459.0 Median 476.5 484.0 486.5 75th % ile 511.5 521.5 534.0

4 Table IV Physical Activity: Total MET Score Females
Baseline Year 1 Year 3 N 298 281 264 Mean (S.D.) 467.1 (43.5) 476.1 (51.3) 479.5 (49.2) 25th % ile 434.0 441.5 446.5 Median 461.5 466.5 477.8 75th % ile 491.5 504.0

5 Table V GEE Models Relationship of Physical Activity with Selected Outcomes Adjusted for Visit, Gender and Tanner Stage Parameter * Estimate (also adjusted for BMI) (S.E.) Z-Value Prob. Systolic B.P. Total MET (0.0040) -2.89 0.0038 LDL-Cholesterol (0.0078) -1.64 0.1014 BMI Intense (0.0121) -1.85 0.0643 * Parameter estimates represent effect of one hour/week of physical activity on indicated outcome

6 Figure 1 Mean Hours/Week of Intense Activity

7 Figure 2 Mean Hours/Week of Moderate Activity

8 Figure 3 Mean Change in Met Score


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