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Extramedullary Plasmacytoma Arising From the Anterior Mediastinum

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1 Extramedullary Plasmacytoma Arising From the Anterior Mediastinum
Kiyoshi Sato, PhD, Satoshi Fumimoto, MD, Takehisa Fukada, MD, Yoshio Ichihashi, MD, Kaoru Ochi, MD, Hidetoshi Satomi, MD, Takuya Morita, PhD, Nobuharu Hanaoka, PhD, Yoshikatsu Okada, PhD, Takahiro Katsumata, PhD  The Annals of Thoracic Surgery  Volume 103, Issue 5, Pages e393-e395 (May 2017) DOI: /j.athoracsur Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 (A) A chest roentgenogram shows a solitary mass in the left upper mediastinal area. (B) A chest computed tomography scan shows the lesion, measuring 40 × 40 mm, is adjacent to the aortic arch with a homogeneous inner component in the left anterior mediastinum. The Annals of Thoracic Surgery  , e393-e395DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 A 18F-Fluorodeoxyglucose positron emission tomography image shows high accumulation in the mediastinal lesion, with a maximum standardized uptake value of 9.0. The Annals of Thoracic Surgery  , e393-e395DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Microscopic examination show diffuse infiltrates of plasma cells with eccentric, occasional variably enlarged nuclei with abundant cytoplasm (hematoxylin and eosin stain, original magnification ×200). (A) Immunohistochemical staining shows that the neoplastic plasma cells (B) were strongly positive for CD138 and (C) had kappa monoclonality (immunohistochemical stain; CD138 original magnification ×200 and kappa light chain original magnification ×200.) The Annals of Thoracic Surgery  , e393-e395DOI: ( /j.athoracsur ) Copyright © 2017 The Society of Thoracic Surgeons Terms and Conditions

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