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Figure 1 ASO functions ASO functions Target mRNA fates depending on ASO mechanism of action that is determined by where the ASO is targeted and by ASO.

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Presentation on theme: "Figure 1 ASO functions ASO functions Target mRNA fates depending on ASO mechanism of action that is determined by where the ASO is targeted and by ASO."— Presentation transcript:

1 Figure 1 ASO functions ASO functions Target mRNA fates depending on ASO mechanism of action that is determined by where the ASO is targeted and by ASO chemistry. ASO = antisense oligonucleotide; DMD = Duchenne muscular dystrophy; ESE = exonic splicing enhancer; ISS = intronic splicing silencer; LncRNA = long noncoding RNA; SMN = survival motor neuron. Daniel R. Scoles et al. Neurol Genet 2019;5:e323 Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.


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