1. WALT know diabetes. Type 1 diabetes Type 2 diabetes
Usually develops before the age of 20, with a peak at 12 years old.
Usually appears after the age of 40.
Pancreas stops making insulin, is an auto-
immune disorder.
Pancreas makes reduced amounts of insulin, or the body does not respond normally to the insulin produced.
Treatments include insulin injections, diet control and regular exercise.
Treatments include diet control, medication and regular exercise.
About 10% of diabetes cases.
About 90% of cases.
Also called insulin-dependent diabetes mellitus (IDDM)
Also called non-insulin dependent diabetes
Symptoms: develops quickly, tiredness, excessive urine production, weight loss, increased thirst and blurred vision.
Symptoms: slow development, same as for type 1 but less severe and may go undetected for many years.

2. Clicker question
ADH (anti-diuretic hormone)is a hormone that regulates the kidneys
to maintain the water balance in our body.
ADH is produced by the pituitary gland and functions in a negative
loop mechanism.
When you sweat a lot, the ADH travels in the blood
to your kidneys and affect the tubules so that more water
is absorbed by your cells. This results in concentrated and
small amount of urine. The opposite happens when you don‘t
lose too much water, for example on a cold day.
Alcohol reduces the amount of ADH produced. This results in…
producing lots of urine
producing less urine
feeling hungry
feeling tired

3. Oral glucose tolerance test
Graph shows the result of an oral glucose tolerance test. This test is used to diagnose diabetes.
Two patients were given a glucose drink (75g) after fasting overnight and their blood glucose
level was measured for the next 2 hours.
The x-axis refers to minutes and the y-axis refers to blood glucose concentration (mM/L).
Which is the healthy patient and which is the diabetic patient?
Why do you think so? Explain you answer.

4. WALT know homeostasis https://www.youtube.com/watch?v=quQr6X1Q58I
 Task : Explain in your own words what homeostasis is.

6. Watch :
how beta cells produce insulin
how insulin functions
Extra time :

7. Glut 4 – transporter protein
Source : austincc.edu