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Published byReynard Daniel Cross Modified over 5 years ago
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Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine‐resistant malaria The PPPK‐dhps enzyme is expressed in clones containing the integrated mutant dhps alleles. Proteins from synchronized trophozoites were separated by SDS–PAGE and blotted to nitrocellulose. The upper filter was probed with anti‐dhps antibodies and the lower filter with antibodies to the P.falciparum hsp70 protein. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER. EMBO J, Volume: 17, Issue: 14, Pages: , First published: 15 July 1998, DOI: ( /emboj/ )
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