1. Dysproteinemia-related nephropathy associated with crystal-storing histiocytosis 
M.B. Stokes, B. Aronoff, D. Siegel, V.D. D'Agati 
Kidney International 
Volume 70, Issue 3, Pages (August 2006)
DOI: /sj.ki
Copyright © 2006 International Society of Nephrology Terms and Conditions

2. Figure 1
Fractured, eosinophilic cast (myeloma cast) surrounded by mononuclear cells (arrow) (hematoxylin and eosin stain; original magnification × 600).
Kidney International  , DOI: ( /sj.ki )
Copyright © 2006 International Society of Nephrology Terms and Conditions

3. Figure 2
Tubular epithelium displays eosinophilic needle-shaped intracytoplasmic crystalline inclusions (arrow) (hematoxylin and eosin stain; original magnification × 1000).
Kidney International  , DOI: ( /sj.ki )
Copyright © 2006 International Society of Nephrology Terms and Conditions

4. Figure 3
Numerous interstitial cells display eosinophilic needle-shaped intracytoplasmic crystalline inclusions (hematoxylin and eosin stain; original magnification × 1000).
Kidney International  , DOI: ( /sj.ki )
Copyright © 2006 International Society of Nephrology Terms and Conditions

5. Figure 4
Interstitial cells stain for CD68 confirming histiocytic phenotype. Some of these cells display intracytoplasmic crystals (arrow) (immunoperoxidase stain, original magnification × 600).
Kidney International  , DOI: ( /sj.ki )
Copyright © 2006 International Society of Nephrology Terms and Conditions

6. Figure 5
Electron microscopy demonstrates rod-shaped and rhomboid-shaped intracytoplasmic crystalline inclusions within tubular epithelium (electron micrograph; original magnification × 4000).
Kidney International  , DOI: ( /sj.ki )
Copyright © 2006 International Society of Nephrology Terms and Conditions

7. Figure 6
Tubular epithelium contains intracytoplasmic rhomboid-shaped electron-dense crystalline structures, focally accompanied by a unit membrane (arrow) (electron micrograph; original magnification × 12 000).
Kidney International  , DOI: ( /sj.ki )
Copyright © 2006 International Society of Nephrology Terms and Conditions