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Volume 62, Issue 6, Pages (December 2002)

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Presentation on theme: "Volume 62, Issue 6, Pages (December 2002)"— Presentation transcript:

1 Volume 62, Issue 6, Pages 2152-2159 (December 2002)
Association between hypertension and variation in the α- and β-adducin genes in a white population  Ji-Guang Wang, Jan A. Staessen, Cristina Barlassina, Robert Fagard, Tatiana Kuznetsova, Harry A. Struijker-Boudier, Laura Zagato, Lorena Citterio, Elisabetta Messaggio, Giuseppe Bianchi  Kidney International  Volume 62, Issue 6, Pages (December 2002) DOI: /j x Copyright © 2002 International Society of Nephrology Terms and Conditions

2 Figure 1 Risk of hypertension in β-adducin T allele carriers versus CC homozygotes in men and women, in users (OC+) and non-users (OC-) of oral contraceptives and in post-menopausal women. Squares represent odds ratios adjusted for age, age2, body-mass index, smoking, alcohol intake and, in all women, for the use of oral contraceptives. The size of the squares is proportional to the number of cases given alongside the symbols. Vertical lines denote 95% confidence intervals. Number of subjects (N) and significance levels for odds ratios (P) and for the sex-by-genotype interaction (P-int) are given. Kidney International  , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions

3 Figure 2 Urinary Na+/K+ ratio by β-adducin genotype in users (OC+) and non-users (OC-) of oral contraceptives and in post-menopausal women. Circles (CC genotype) and dots (T allele carriers) represent means adjusted for age and body-mass index. Vertical lines denote SEs. Number of subjects (N) and significance levels (P) for the differences between T allele carriers and CC homozygotes are given. Kidney International  , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions


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