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Cardiac Resynchronization Therapy: Long-Term Alternative to Cardiac Transplantation?  Bert Hansky, MD, Jürgen Vogt, MD, Armin Zittermann, PhD, Holger Güldner,

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Presentation on theme: "Cardiac Resynchronization Therapy: Long-Term Alternative to Cardiac Transplantation?  Bert Hansky, MD, Jürgen Vogt, MD, Armin Zittermann, PhD, Holger Güldner,"— Presentation transcript:

1 Cardiac Resynchronization Therapy: Long-Term Alternative to Cardiac Transplantation? 
Bert Hansky, MD, Jürgen Vogt, MD, Armin Zittermann, PhD, Holger Güldner, MD, Johannes Heintze, MD, Uwe Schulz, MD, Dieter Horstkotte, MD, PhD, Gero Tenderich, MD, PhD, Reiner Körfer, MD, PhD  The Annals of Thoracic Surgery  Volume 87, Issue 2, Pages (February 2009) DOI: /j.athoracsur Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Kaplan–Meier estimates of freedom from therapy failure in cardiac transplant candidates with cardiac resynchronization therapy. Dotted lines indicate 95% confidence intervals. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Time course of various outcome variables during the first 6 months of cardiac resynchronization therapy in cardiac transplant candidates who survived (N = 381) or did not survive (N = 111) during follow-up. The two-factor repeated-measures analysis of variance revealed significant time effects for New York Heart Association (NYHA) class (p < 0.001), maximal oxygen consumption (V̇o2max; p < 0.001), 6-minute hall-walk distance (p < 0.001), and left ventricular end-diastolic diameter (LVEDD; p < 0.001). Significant differences between groups were present for New York Heart Association class (p < 0.05), maximal oxygen consumption (p < 0.01), 6-minute hall-walk distance (p < 0.01), and left ventricular end-diastolic diameter (p < 0.001). *p < 0.05; **p < 0.01; ***p < between patients with and without an event during follow-up. (BL = baseline.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Allocation scheme for cardiac resynchronization therapy (CRT) or cardiac transplantation (CTx). (VAD = ventricular assist device.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

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