1. COPD Guidelines: A Review of the 2018 GOLD Report
Shireen Mirza, MBBS, Ryan D. Clay, MD, Matthew A. Koslow, MD, Paul D. Scanlon, MD 
Mayo Clinic Proceedings 
Volume 93, Issue 10, Pages (October 2018)
DOI: /j.mayocp
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2. Figure 3
Proposed step-wise algorithm based on usual clinical practice. aICS = inhaled corticosteroid; LABA = long-acting beta agonist; LAMA = long-acting muscarinic antagonist; SABA = short-acting beta agonist; SAMA = short-acting muscarinic antagonist. bRoflumilast may be considered for patients with severe-very severe obstruction with chronic bronchitis and frequent exacerbations. cMucolytics may be considered in patients with chronic bronchitis and frequent exacerbations. dAzithromycin may be considered for reduction of exacerbations in former smokers over age 65 and mild airflow obstruction. eAvoid routine concomitant SAMA use when on LAMA.
Mayo Clinic Proceedings  , DOI: ( /j.mayocp )
Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions