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Volume 30, Issue 3, Pages (September 2016)

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Presentation on theme: "Volume 30, Issue 3, Pages (September 2016)"— Presentation transcript:

1 Volume 30, Issue 3, Pages 501-503 (September 2016)
An Integrated Model of RAF Inhibitor Action Predicts Inhibitor Activity against Oncogenic BRAF Signaling  Zoi Karoulia, Yang Wu, Tamer A. Ahmed, Qisheng Xin, Julien Bollard, Clemens Krepler, Xuewei Wu, Chao Zhang, Gideon Bollag, Meenhard Herlyn, James A. Fagin, Amaia Lujambio, Evripidis Gavathiotis, Poulikos I. Poulikakos  Cancer Cell  Volume 30, Issue 3, Pages (September 2016) DOI: /j.ccell Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 The OUT Position of the αC Helix Stabilized by Inhibitor Is the Structural Basis of Resistance of Dimeric RAF to RAF Inhibitors (corrected) Cancer Cell  , DOI: ( /j.ccell ) Copyright © 2016 Elsevier Inc. Terms and Conditions

3 Figure 1 The OUT Position of the αC Helix Stabilized by Inhibitor Is the Structural Basis of Resistance of Dimeric RAF to RAF Inhibitors (original) Cancer Cell  , DOI: ( /j.ccell ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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