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OOGENESIS DR.SHABANA ALI
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FEMALE REPRODUCTIVE SYSTEM
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INTRAUTERINE LIFE 2nd wk..yolk sac 5th wk…gonades 3rd_5thmonth ..mitosis 7thmonth.. degeneration 40,000 at birth 500 ovulation, One oocyte is released in each cycle
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Primary follicle Secondary follicle
INTRAUTERINE LIFE Primordial follicle meiosis I (prophase)arrest AT PUBERTY Monthly ovarian cycle Primary follicle Secondary follicle Secondary oocyte, One polar body. (ovulation)if fertilization occur mature ovum,polar bodies Resume Meiosis one complete 2nd meiosis Metaphase arrest Meiosis 2 completes
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Ist meiotic divison till prophase .Complets Ist meiotic division
Intrauterine life Primordial follicle At puberty Primary follicle Secondary follicle Primary oocytes Secondary oocyte Ist meiotic divison till prophase .Complets Ist meiotic division .Starts 2nd meiotic division till metaphase
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Every month,15-20 follicles are selected and they mature in three stages
1.primary/preantral 2.secondary/antral-longest 3.preovulatory-37 hrs before ovulation
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INTRAUTERINE LIFE
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PRIMORDIAL FOLLICLE 1.Primary oocyte 2.flat cell layer
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PRIMARY FOLLICLE 1.granulosa cells..stratfied cuboidal cells
2.zona pellucida..Acelluler,glyco protein layer,impermeable 3.theca folliculi…theca externa and interna
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SECONDARY FOLLICLE 1.Antrum 2.cumulus oophorus 3.size-increased
4.25mm in size
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CORPUS LUTEUM 1.cell number increased 2.vascularity increased
3.size… more than 25mm
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CORPUS ATRETICUM 1.cell number decreased 2.vascularity decreased
3.degeneration
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CORPUS ALBICAN 1.Fatty degeneration of cells 2.Fibrous tissue
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Gonadotropins, Hormones, and the Ovarian and Uterine Cycles
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Pituitary-Ovarian Axis
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oogenesis
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