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Published byCornelia Park Modified over 5 years ago
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Treating insect bite hypersensitivity in horses by using active vaccination against IL-5
Albert Y. Wu, MD, Sanjiv Sur, MD, J. Andrew Grant, MD Journal of Allergy and Clinical Immunology Volume 142, Issue 4, Pages (October 2018) DOI: /j.jaci Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions
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Fig 1 A, Biologic treatment with mAbs (eg, mepolizumab, reslizumab, and benralizumab) has been used to target IL-5 or the IL-5 receptor in the setting of a variety of eosinophilic disorders. B, A horse vaccine (eIL-5–CMVTT) was able to elicit autoantibodies with the same therapeutic target and improve IBH skin lesions. Ab, Antibody; IL-5R, IL-5 receptor. Journal of Allergy and Clinical Immunology , DOI: ( /j.jaci ) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions
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