1. Figure 1. Schematic diagram of MR analysis to estimate expected association for genotypes (SNPs) with the trait of insulin resistance. The underlying assumption of MR analysis is that the genotype and phenotype association is independent of confounding factors. MR, Mendelian randomization; SNP, single nucleotide polymorphism; HOMA-IR, homeostatic model assessment for insulin resistance; T2DM, type 2 diabetes mellitus.
Figure 1. Schematic diagram of MR analysis to estimate expected association for genotypes (SNPs) with the trait of insulin resistance. The underlying assumption of MR analysis is that the genotype and phenotype association is independent of confounding factors. MR, Mendelian randomization; SNP, single nucleotide polymorphism…
J Lipid Atheroscler. 2019;8:e8.