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GERARDO COLON-OTERO, M.D.  Mayo Clinic Proceedings 

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Presentation on theme: "GERARDO COLON-OTERO, M.D.  Mayo Clinic Proceedings "— Presentation transcript:

1 Peripheral T-Cell Lymphoma Simulating Hodgkin's Disease With Initial Bone Marrow Involvement 
GERARDO COLON-OTERO, M.D.  Mayo Clinic Proceedings  Volume 61, Issue 1, Pages (January 1986) DOI: /S (12) Copyright © 1986 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Fig. 1 Bone marrow biopsy specimen, showing neoplastic giant cells with multiple nuclear lobes and macronucleoli, features initially interpreted as diagnostic of Hodgkin's disease. (Hematoxylin and eosin; ×640.) Mayo Clinic Proceedings  , 68-71DOI: ( /S (12) ) Copyright © 1986 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Fig. 2 A, Inguinal lymph node biopsy specimen, showing partial preservation of normal functional cellular components and paracortical zones of heterogeneous neoplastic cellularity (arrows). (Hematoxylin and eosin; ×40.) B, Higher-magnification appearance of neoplastic paracortical process, with giant cells surrounded by atypical mononuclear forms. Note that even medium and small-sized lymphocytes contain complex, irregularly shaped nuclei, in contrast to benign, normal-appearing lymphoid background characteristic of Hodgkin's disease. (Hematoxylin and eosin; ×640.) Mayo Clinic Proceedings  , 68-71DOI: ( /S (12) ) Copyright © 1986 Mayo Foundation for Medical Education and Research Terms and Conditions


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