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Antibodies to interleukin-8 and paraneoplastic catastrophic recurrent thromboses  Emmanuel de Maistre, MD, Véronique Regnault, PhD, Thomas Lecompte, MD,

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Presentation on theme: "Antibodies to interleukin-8 and paraneoplastic catastrophic recurrent thromboses  Emmanuel de Maistre, MD, Véronique Regnault, PhD, Thomas Lecompte, MD,"— Presentation transcript:

1 Antibodies to interleukin-8 and paraneoplastic catastrophic recurrent thromboses 
Emmanuel de Maistre, MD, Véronique Regnault, PhD, Thomas Lecompte, MD, Philippe Scheid, MD, Yves Martinet, MD, PhD, Abdel Bellou, MD, Jean Amiral, PhD, Anne-Marie Vissac  The American Journal of Medicine  Volume 111, Issue 7, Pages (November 2001) DOI: /S (01)

2 Figure 1 Detection of anti-interleukin-8 (IL-8) antibodies using surface plasmon resonance spectroscopy. IL-8 was covalently immobilized on the biosensor surface. After 100 seconds, plasma was injected, followed by the injection of either anti-IgG or anti-IgM antibodies after 500 seconds. The initial abrupt change in the signal level at the start and the end of the injection is due to the refractive index difference between running buffer and plasma. The American Journal of Medicine  , DOI: ( /S (01) )

3 Figure 2 Inhibition of antibody binding to immobilized IL-8 is represented as a function of soluble IL-8 added to plasma. The American Journal of Medicine  , DOI: ( /S (01) )


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