1. The Lancet Infectious Diseases
Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study 
Rob W van der Pluijm, MD, Prof Mallika Imwong, PhD, Nguyen Hoang Chau, MD, Nhu Thi Hoa, MD, Nguyen Thanh Thuy-Nhien, PhD, Ngo Viet Thanh, MD, Podjanee Jittamala, MD, Borimas Hanboonkunupakarn, MD, Kitipumi Chutasmit, MD, Chalermpon Saelow, MD, Ratchadaporn Runjarern, MD, Weerayuth Kaewmok, MD, Rupam Tripura, MD, Thomas J Peto, PhD, Sovann Yok, MD, Seila Suon, MD, Sokunthea Sreng, Sivanna Mao, MD, Savuth Oun, MD, Sovannary Yen, MD, Chanaki Amaratunga, PhD, Dysoley Lek, MD, Rekol Huy, MD, Mehul Dhorda, PhD, Prof Kesinee Chotivanich, PhD, Elizabeth A Ashley, MBBS, Mavuto Mukaka, PhD, Naomi Waithira, MSc, Phaik Yeong Cheah, PhD, Richard J Maude, DPhil, Roberto Amato, PhD, Richard D Pearson, PhD, Sónia Gonçalves, PhD, Christopher G Jacob, PhD, William L Hamilton, PhD, Rick M Fairhurst, MD, Prof Joel Tarning, PhD, Markus Winterberg, PhD, Prof Dominic P Kwiatkowski, FRS, Prof Sasithon Pukrittayakamee, DPhil, Prof Tran Tinh Hien, MD, Prof Nicholas PJ Day, FMedSci, Prof Olivo Miotto, PhD, Prof Nicholas J White, FRS, Prof Arjen M Dondorp, MD 
The Lancet Infectious Diseases 
DOI: /S (19)
Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4·0 license Terms and Conditions

2. Figure 1
Kaplan-Meier survival curves of PCR-corrected efficacy of dihydroartemisin-piperaquine by (A) study site, (B) crt mutation status, and (C) plasmepsin-2 and plasmepsin-3 amplification status
Other crt alleles indicate parasites carrying no mutations at positions 93, 97, 145, 218, 343, and 353 of the crt gene. Infections caused by parasites with a Met343Ile or Gly353Val crt mutation were too scarce to be included in survival curves by crt mutation status.
The Lancet Infectious Diseases DOI: ( /S (19) )
Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4·0 license Terms and Conditions

3. Figure 2
kelch13 mutation status, plasmepsin2/3 amplification status, and crt mutation status by site and country in the TRACI and TRACII trials
(A) KelchX mutation status indicates parasites with a kelch13 mutation other than Cys580Tyr. (B) Single amplification status indicates parasites without a plasmepsin-2 and plasmepsin-3 amplification. (C) Other crt alleles indicate parasites carrying no mutations at positions 93, 97, 145, 218, 343, and 353 of the crt gene.
The Lancet Infectious Diseases DOI: ( /S (19) )
Copyright © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4·0 license Terms and Conditions