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MRI in autosomal recessive hereditary spastic paraplegia: high T2 signal intensity in periventricular white matter and corona radiata with thin corpus.

Published bySturla Carlsson Modified over 5 years ago

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Presentation on theme: "MRI in autosomal recessive hereditary spastic paraplegia: high T2 signal intensity in periventricular white matter and corona radiata with thin corpus."— Presentation transcript:

1 MRI in autosomal recessive hereditary spastic paraplegia: high T2 signal intensity in periventricular white matter and corona radiata with thin corpus callosum. MRI in autosomal recessive hereditary spastic paraplegia: high T2 signal intensity in periventricular white matter and corona radiata with thin corpus callosum. Reprinted with permission from Hourani R, et al. Am J Neuroradiol 2009;30(5):936–40. DOI: Lina Nashef et al. Pract Neurol 2019;19: ©2019 by BMJ Publishing Group Ltd

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(A) Diffusion-tensor imaging assessment of white matter damage after traumatic brain injury (TBI). (A) Diffusion-tensor imaging assessment of white matter.

(A) Diffusion-tensor imaging assessment of white matter damage after traumatic brain injury (TBI). (A) Diffusion-tensor imaging assessment of white matter.
Figure 1. MRI features of AP5Z1-associated complicated spastic paraplegia MRI features of AP5Z1-associated complicated spastic paraplegia (A) Periventricular.

Figure 1. MRI features of AP5Z1-associated complicated spastic paraplegia MRI features of AP5Z1-associated complicated spastic paraplegia (A) Periventricular.
OCT left eye (case 3). OCT showed bilateral foveal atrophy (white arrows), with an island of preserved retina in the left fovea (yellow arrow; only left.

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A, ROIs that were drawn in the flow territories of the anterior cerebral artery (cortex: ROIs 1 and 2, basal ganglia: ROIs 5 and 6) and the middle cerebral.

A, ROIs that were drawn in the flow territories of the anterior cerebral artery (cortex: ROIs 1 and 2, basal ganglia: ROIs 5 and 6) and the middle cerebral.
A case with near-occlusion with full collapse, reprinted with permission from Fox et al.1 Lateral common carotid angiogram shows the thin, threadlike,

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A–C, Case 1. A–C, Case 1. Typical white matter changes involving the corpus callosum and the pyramidal tracts (A and C, arrows), dilation of the lateral.

A–C, Case 1. A–C, Case 1. Typical white matter changes involving the corpus callosum and the pyramidal tracts (A and C, arrows), dilation of the lateral.
Masashi Maeda et al. Heart Asia 2013;5:7-14

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Detection of microemboli by transcranial Doppler identifies high-risk asymptomatic carotid stenosis. Detection of microemboli by transcranial Doppler identifies.

Detection of microemboli by transcranial Doppler identifies high-risk asymptomatic carotid stenosis. Detection of microemboli by transcranial Doppler identifies.
Figure 2 Specific brain MRI findings of 8 patients

Figure 2 Specific brain MRI findings of 8 patients
Case one: (A and B) Right and left colour fundus photographs of the optic nerve head showing small crowded discs with anomalous branching of the blood.

Case one: (A and B) Right and left colour fundus photographs of the optic nerve head showing small crowded discs with anomalous branching of the blood.
Photograph of the legs of a patient with inherited erythromelalgia, showing erythema to the level of the mid-calf. Photograph of the legs of a patient.

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MRI scans show coronal sections of the brain and right hippocampus at baseline, 9 months, 2 years (when he was diagnosed with mild cognitive impairment)

MRI scans show coronal sections of the brain and right hippocampus at baseline, 9 months, 2 years (when he was diagnosed with mild cognitive impairment)
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Figure 1 Family pedigree and MRI

Figure 1 Family pedigree and MRI
Diffusion-weighted (TR = 3900, TE = 94, B = 1000, number of gradient directions = 90) imaging (A) with corresponding apparent diffusion coefficient map.

Diffusion-weighted (TR = 3900, TE = 94, B = 1000, number of gradient directions = 90) imaging (A) with corresponding apparent diffusion coefficient map.
Susceptibility-weighted MRI of ex vivo hippocampal tissue.

Susceptibility-weighted MRI of ex vivo hippocampal tissue.
Photograph of the legs of a patient with inherited erythromelalgia, showing erythema to the level of the mid-calf. Photograph of the legs of a patient.

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Injection sites for greater occipital nerve (GON) block.

Injection sites for greater occipital nerve (GON) block.

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