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Variable CD7 Expression on T Cells in the Leukemic Phase of Cutaneous T Cell Lymphoma (Sézary Syndrome) Eric C. Vonderheid, Amy Kotecha, Christine M. Boselli Journal of Investigative Dermatology Volume 117, Issue 3, Pages (September 2001) DOI: /j x Copyright © 2001 The Society for Investigative Dermatology, Inc Terms and Conditions
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Figure 1 Distribution of CD7 expression in leukemic phase CTCL studied at MCP Hahnemann University. The percentage of CD7 expression by blood lymphocytes of 42 patients with leukemic phase of CTCL does not deviate significantly from the expected value of a normal distribution (Kolmogorov–Smirnov distribution, 0.127; p=0.09). Journal of Investigative Dermatology , DOI: ( /j x) Copyright © 2001 The Society for Investigative Dermatology, Inc Terms and Conditions
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Figure 2 Distribution of CD7 expression in leukemic phase CTCL studied at the University of Turin. Compared with the results shown in Figure 1, the distribution of CD7 expression by blood lymphocytes of 27 patients with Sézary syndrome with CD4/CD8 ratio=10 who were studied at the University of Turin shows a greater proportion of cases with low CD7 expression (Kolmogorov–Smirnov distribution, 0.127; p=0.009). Journal of Investigative Dermatology , DOI: ( /j x) Copyright © 2001 The Society for Investigative Dermatology, Inc Terms and Conditions
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Figure 3 Dot plot shows two lymphocyte populations in Sézary syndrome. Two populations of malignant lymphocytes are identified on the flow scattergram for patient 37 (small cells in the box designated by the S arrow, large cells in the box designated by the L arrow). The large cell component represents 40.6% of all lymphocytes. Journal of Investigative Dermatology , DOI: ( /j x) Copyright © 2001 The Society for Investigative Dermatology, Inc Terms and Conditions
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