1. Where Does Anticholinergic Therapy Fit in Moderate to Severe Asthma?

3. Introduction

4. Introduction (cont)

5. Uncontrolled Severe Asthma Is a Significant Problem

6. Asthma in Europe

7. Prevalence of Asthma in Children

8. Uncontrolled Asthma Checklist

9. Adults and Adolescents 12 Years and Older

10. Adults and Adolescents 12 Years and Older (cont)

11. AEs of OCSs

12. Children 6 to 11 Years Old

13. Adverse Outcomes from OCS: Long-Term Observational Study

14. AEs of OCSs

15. Tiotropium in Asthma Poorly Controlled With ICS/LABA

16. Tiotropium in Asthma Poorly Controlled With ICS/LABA (cont)

17. Tiotropium or Salmeterol as Add-On Therapy to ICS for Moderate Symptomatic Asthma

18. Tiotropium or Salmeterol as Add-On Therapy to ICS for Moderate Symptomatic Asthma (cont)

19. Tiotropium in Symptomatic Asthma Despite Low- to Medium-Dose ICS

20. Tiotropium Efficacy

21. Tiotropium Safety

22. Adults and Adolescents 12 Years and Older

23. Uncontrolled Asthma Checklist

24. How to Improve Adherence

25. What Are the Possible Reasons for Poor Disease Control?

26. Odds Ratio of an Acute Response to a Short-Acting Bronchodilator to Predict a Clinical Response to a Long-Acting Bronchodilator

27. Adults and Adolescents 12 Years and Older

28. Conclusions