1. Taste cell responses (ΔCa2+) evoked by umami and salty taste stimuli, recorded in a slice preparation of the mouse circumvallate papilla.
Taste cell responses (ΔCa2+) evoked by umami and salty taste stimuli, recorded in a slice preparation of the mouse circumvallate papilla. Taste cells were stimulated sequentially with four salt compounds, all at 500 mm. A, Sequential responses of one taste cell. NaCl, MSG, MPG, and potassium gluconate were applied focally and transiently onto the chemosensitive apical tip of taste buds, as shown by short bars below the traces. The Na+ (i.e., NaCl, MSG traces) and the glutamate (i.e., MSG, MPG traces) moieties both evoked responses in this cell. B, The same sequence of taste stimuli, applied to another taste cell, produced Ca2+ responses from the glutamate moiety alone.
Yutaka Maruyama et al. J. Neurosci. 2006;26:
©2006 by Society for Neuroscience