1. The Semantic Shift Guillaume Mazieres EVP, North American Operations
Klopotek User Group
Orlando, September 20th, 2012

2. TEMIS Semantic Content Enrichment pioneer since 2000 65 26 patents
Heidelberg
Montreal
Paris
New York
Grenoble
Content
Enrichment
London
26 patents

3. 46% semantically enrich their content
Publishers of Scientific Journals
Source : study by the Publishing Research Consortium

4. What is semantic enrichment?

5. What is Semantic Content Enrichment?
The automated extraction of domain metadata
Attributes
Roles
Adverse Event
Side Effect Alopecia
Cause Carbamazepine
Dosage 8.6 mg/ml
Patient 52 year old male
Relations
We report a 52 year-old man presenting an acute hair loss induced by carbamazepine (CBZ) in concentration of 8.6 microg/ml.
Verb
Patient
Symptom
Dosage information
Subj
Entities
Drug Name
Terms
Pro
Verb
Num
Art
N-P
Noun
Adj Nn Pp
PropNn
Unit
Abbr
We report a 52 year-old man presenting an acute hair loss induced by carbamazepine (CBZ) in concentration of 8.6 microg/ml.

6. What is Semantic Content Enrichment?
Document annotation
Alopecia
Dermatitis
Allergic reaction
Anagen effluvium
Telogen effluvium
Symptoms
A case of hair loss induced by carbamazepine
Kohno Y, Ishii A, Shoji S, Department of Clinical Neurology, Tsukuba University.
We report a 52 year-old man presenting with an acute considerable hair loss induced by carbamazepine (CBZ). The remarkable scalp hair loss started within a week after CBZ administration. There was no evidence of dermatitis or allergic reaction, or other cause for the hair loss. The serum concentration of CBZ was 8.6 microg/ml therapeutic range 8-12 microg/ml). CBZ was discontinued, and the hair loss stopped within several days with new hair growth. Medication-induced hair loss is an occasional adverse effect of many drugs used for neuropsychological diseases. CBZ also induces hair loss and its frequency was reported below 2%. Only a limited number of detailed case reports describing CBZ-induced hair loss were available, and we found these cases could divide into two groups with regard to a delay in starting hair loss after administration of CBZ. In one group, the hair loss started within a week suggesting anagen effluvium and in another it started after two or three months suggesting telogen effluvium. This finding suggests the causative mechanism of CBZ-induced hair loss is not unitary.
A case of hair loss induced by carbamazepine Kohno Y, Ishii A, Shoji S, Department of Clinical Neurology, Tsukuba University. We report a 52 year-old man presenting with an acute considerable hair loss induced by carbamazepine (CBZ). The remarkable scalp hair loss started within a week after CBZ administration. There was no evidence of dermatitis or allergic reaction, or other cause for the hair loss. The serum concentration of CBZ was 8.6 microg/ml therapeutic range 8-12 microg/ml). CBZ was discontinued, and the hair loss stopped within several days with new hair growth. Medication-induced hair loss is an occasional adverse effect of many drugs used for neuropsychological diseases. CBZ also induces hair loss and its frequency was reported below 2%. Only a limited number of detailed case reports describing CBZ-induced hair loss were available, and we found these cases could divide into two groups with regard to a delay in starting hair loss after administration of CBZ. In one group, the hair loss started within a week suggesting anagen effluvium and in another it started after two or three months suggesting telogen effluvium. This finding suggests the causative mechanism of CBZ-induced hair loss is not unitary.
Carbamazepine
CBZ
Drugs
Dept of Clinical Neurology, Tsukuba University
Organizations
Kohno Y
Ishii A
Shoji S
People
Neuropsychological diseases
Diseases
man
52 year old
Patient information
Side-effect Relationships
Drug-induced alopecia
8.6 microg./ml
Dosage information
8-12 microg./ml

7. What is Semantic Content Enrichment?
Knowledge insertion
Carbamazepine
Brand names
Apo-Carbamazepine
Atretol
Biston
Calepsin […]
Dosage forms Suspension Oral
Tablet Oral […]
Accession Number DB00564 (APRD00337)
Indication For the treatment of epilepsy and pain associated with true trigeminal neuralgia.
Pharmacodynamics Carbamazepine, an anticonvulsant structurally similar to tricyclic antidepressants, is used to treat partial seizures, tonic-clonic seizures, pain of neurologic origin such as trigeminal neuralgia, and psychiatric disorders including manic-depressive illness […]
Toxicity Mild ingestions cause vomiting, drowsiness, ataxia, slurred speech, nystagmus, dystonic reactions, and hallucinations. Severe intoxications may produce […]
A case of hair loss induced by carbamazepine
Kohno Y, Ishii A, Shoji S, Department of Clinical Neurology, Tsukuba University.
We report a 52 year-old man presenting with an acute considerable hair loss induced by carbamazepine (CBZ). The remarkable scalp hair loss started within a week after CBZ administration. There was no evidence of dermatitis or allergic reaction, or other cause for the hair loss. The serum concentration of CBZ was 8.6 microg/ml therapeutic range 8-12 microg/ml). CBZ was discontinued, and the hair loss stopped within several days with new hair growth. Medication-induced hair loss is an occasional adverse effect of many drugs used for neuropsychological diseases. CBZ also induces hair loss and its frequency was reported below 2%. Only a limited number of detailed case reports describing CBZ-induced hair loss were available, and we found these cases could divide into two groups with regard to a delay in starting hair loss after administration of CBZ. In one group, the hair loss started within a week suggesting anagen effluvium and in another it started after two or three months suggesting telogen effluvium. This finding suggests the causative mechanism of CBZ-induced hair loss is not unitary.
Insert related knowledge
Prior and Authoritative
Internal / Proprietary
External / Commercial or Open Source

8. In a Larger Sense Adding value to content Analytics Linking
Similar
Documents
Patents by
same authors
Adding value to content
Clinical reports for CBZ
Analytics
Articles on other drugs inducing alopecia
Linking
Knowledge Insertion
Annotation
man/52-year old/Patient information
Carbamazepine/Drug
Alopecia/Symptom
Drug-induced Alopecia/Side-effect
Raw Document

9. Who’s using it?
And for which purpose?

13. « Slice and Dice » approach Chapters from books and articles from journals are available on an individual basis

14. Article Profile
Summarizes all relevant entities mentioned
Entities are clickable to facilitate navigation
Recommendation Widgets
Provide links to related assets

15. Topical Feed
Aggregates all articles referring to a specific pricing location

16. Editorial Productivity
Automated indexing of 2M BIOSIS abstracts 5 months vs. 2,000 man months (manual)
x4 Volume of indexed documents (stable indexing team size)
95% Automated linking of legal citations Anonymization of case law

17. Semantic Content Enrichment
Benefits for Information Access
Makes highly relevant content highly findable
Improves precision and recall of search engines
Boosts the quality of search results
Facilitates exploration
Powers facets
Provides navigational cues
Adds value to the original content
Provides context by linking to related documents and knowledge
Provides perspective by enabling analytics

18. Thank You Your questions Guillaume Mazieres
EVP, North American Operations
Klopotek User Group
Orlando, September 20th,