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Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism Equal amounts of WT cells and indicated single.

Published byUtami Erlin Indradjaja Modified over 5 years ago

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Presentation on theme: "Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism Equal amounts of WT cells and indicated single."— Presentation transcript:

1 Endosome and Golgi‐associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism Equal amounts of WT cells and indicated single or double mutants in serial dilutions were incubated on agar plates at the indicated temperatures. Schematic representation of the topology of Tul1. Phylogenetic tree of selected Tul1 orthologs. Ultrafast bootstrap (UFboot) values are indicated on the branches. Multiple alignment of the Tul1 RING finger domain. UniProt sequence accessions are provided after the species name. For two sequences (Cryptococcus_neoformans_Q5KMZ4, Tetrahymena_thermophila_I7MAJ9), a long insertion was replaced by the number of deleted residues in brackets. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER. EMBO J, Volume: 38, Issue: 15, First published: 27 May 2019, DOI: ( /embj )

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