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Low-grade dysplasia in Barrett’s esophagus

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Presentation on theme: "Low-grade dysplasia in Barrett’s esophagus"— Presentation transcript:

1 Low-grade dysplasia in Barrett’s esophagus
Prateek Sharma  Gastroenterology  Volume 127, Issue 4, Pages (October 2004) DOI: /j.gastro Copyright © 2004 American Gastroenterological Association Terms and Conditions

2 Figure 1 Areas of low-grade dysplasia (LGD) (green arrow) in a biopsy specimen of a patient with Barrett’s esophagus. The nuclei are hyperchromatic, have irregular nuclear contours and are overlapping. This is in contrast to areas without dysplasia (blue arrow). Courtesy of John Goldblum, M.D., Cleveland Clinic, Cleveland, Ohio. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2004 American Gastroenterological Association Terms and Conditions

3 Figure 2 Photomicrograph of a biopsy specimen harboring low-grade dysplasia (LGD), including surface epithelium showing cytological atypia (arrow). Courtesy of John Goldblum, M.D., Cleveland Clinic, Cleveland, Ohio. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2004 American Gastroenterological Association Terms and Conditions

4 Figure 3 Outcome of low-grade dysplasia (LGD) in a large Barrett’s database. The majority of the patients fail to have LGD detected during follow-up. Gastroenterology  , DOI: ( /j.gastro ) Copyright © 2004 American Gastroenterological Association Terms and Conditions


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