1. Fig. 2. Efficacy endpoints among treatment groups: least square (LS) mean changes from baseline in the WOMAC-pain subscale (A), total WOMACOA index score (B), WOMAC-stiffness subscale (C), and WOMAC-physical function subscale (D) at weeks 3 and 6 (intent-to-treat population, baseline observation carried forward). Data shown below the brackets are estimated treatment differences with 95% confidence intervals and p-values. The text in red indicates the upper confidence interval. Noninferiority can be inferred, as the predefined noninferiority margin for the WOMAC-pain subscale (A) was a score of 5 (10% of the total score), total WOMAC-OA index (B) was a score of 24 (10% of the total score), WOMAC-stiffness subscale (C) was a score of 2 (10% of the total score), and WOMAC-physical function subscale (D) was a score of 17 (10% of the total score). WOMAC: Western Ontario and McMaster Universities, OA: osteoarthritis.
Fig. 2. Efficacy endpoints among treatment groups: least square (LS) mean changes from baseline in the WOMAC-pain subscale (A), total WOMACOA index score (B), WOMAC-stiffness subscale (C), and WOMAC-physical function subscale (D) at weeks 3 and 6 (intent-to-treat population, baseline observation carried forward). Data shown below the brackets are…
Clin Orthop Surg Dec;9(4):