Presentation is loading. Please wait.

Presentation is loading. Please wait.

Bovine-Serum-Albumin-Containing Receptor Phase Better Predicts Transdermal Absorption Parameters for Lipophilic Compounds  Sheree E. Cross, Yuri G. Anissimov,

Similar presentations


Presentation on theme: "Bovine-Serum-Albumin-Containing Receptor Phase Better Predicts Transdermal Absorption Parameters for Lipophilic Compounds  Sheree E. Cross, Yuri G. Anissimov,"— Presentation transcript:

1 Bovine-Serum-Albumin-Containing Receptor Phase Better Predicts Transdermal Absorption Parameters for Lipophilic Compounds  Sheree E. Cross, Yuri G. Anissimov, Beatrice M. Magnusson, Michael S. Roberts  Journal of Investigative Dermatology  Volume 120, Issue 4, Pages (April 2003) DOI: /j x Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 kp values for C1-C10 alcohols with water (open symbols) and 4% BSA (closed symbols) as receptor phases. Journal of Investigative Dermatology  , DOI: ( /j x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 Comparison of the SC (circles) and tape-stripped epidermis (squares) to donor solution (fraction remaining at the end of the study) and SC to stripped epidermis (triangles) partitioning for each of the alcohols using water (open symbols) and 4% BSA (closed symbols) receptor phases. Journal of Investigative Dermatology  , DOI: ( /j x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

4 Figure 3 Comparison of the tape-stripped epidermis to receptor phase (fraction penetrated at the end of the study) partitioning for each of the alcohols using water (open symbols) and 4% BSA (closed symbols) receptor phases. Journal of Investigative Dermatology  , DOI: ( /j x) Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions


Download ppt "Bovine-Serum-Albumin-Containing Receptor Phase Better Predicts Transdermal Absorption Parameters for Lipophilic Compounds  Sheree E. Cross, Yuri G. Anissimov,"

Similar presentations


Ads by Google