1. Peptic Ulcer

2. Ulcers: Open sores that develop on the inside lining of the stomach, upper small intestine, or esophagus

3. Peptic Ulcer ©http://images. medicinenet

4. Perforated Stomach from Peptic Ulcer ©http://medicalimages. allrefer

5. Peptic Ulcer

6. Depending on the location, there are different types of ulcers:
Gastric ulcer: peptic ulcer that occurs in the stomach
Duodenal ulcer: occurs in the first part of the small intestine (duodenum)
Esophageal ulcer: usually occurs in the lower part of the esophagus

7. Once believed to have been caused by lifestyle (diet, stress,etc.)

8. Actually caused by a bacteria H. pylori
Bacteria lives and reproduces in the mucus layer that covers and protects the tissue that lines the stomach and intestine
Causes inflammation of the lining and can lead to an ulcer

9. Number one symptom?
Pain

10. Diagnosis
Endoscopy: a long narrow tube attached to a camera is sent down the esophagus

11. Treatment Antibiotics Antacids: neutralize stomach acid
H-2 Blocker (histamine blocker—histamine encourages HCl acid secrection)
Proton Pump Inhibitors: stop the production of acid

12. Peptic Ulcer ©http://images. google. com/imgres. imgurl=http://www

13. Triangle: necrotic fibrinoid debris and nonspecific inflammatory infiltrate Arrow: granulation tissue ©