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A BMPy Road for Venous Development

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Presentation on theme: "A BMPy Road for Venous Development"— Presentation transcript:

1 A BMPy Road for Venous Development
Lauren M. Goddard, Mark L. Kahn  Developmental Cell  Volume 42, Issue 5, Pages (September 2017) DOI: /j.devcel Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Twist1 Coordinates Skull and Venous Development through BMP Signaling Twist1+ osteoprogenitor cells (Osteo-PCs) express BMP2 and BMP4 that act on venous endothelial cells during skull formation (beige). In human craniosynostosis, loss of osteo-PC Twist1 results in defective formation of both the skull and the associated cranial venous system (blue) without disturbing arterial development (red). Developmental Cell  , DOI: ( /j.devcel ) Copyright © 2017 Elsevier Inc. Terms and Conditions


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