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Clinical Challenges in the Transplant-Eligible Patient With Newly Diagnosed Multiple Myeloma.

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Presentation on theme: "Clinical Challenges in the Transplant-Eligible Patient With Newly Diagnosed Multiple Myeloma."— Presentation transcript:

1 Clinical Challenges in the Transplant-Eligible Patient With Newly Diagnosed Multiple Myeloma

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9 Multiple Myeloma Choice of Induction Regimen

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12 Multiple Myeloma Competing Induction Regimens

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14 Choice of Induction Regimen Use the best drugs early to get maximum remission for as long as possible, both for the standard-risk as well as the high-risk patients.

15 Multiple Myeloma Early vs Delayed HDT/ASCT

16 Timing of HDT/ASCT Patients with no high-risk disease, who are responsive and tolerate therapy, may do extremely well with delayed HDT/ASCT.

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18 Multiple Myeloma Maintenance Therapy

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20 Consider No Maintenance For patients with standard-risk disease, stringent CR, normal FLC ratio, who are immunofixation negative in urine and serum, and have completely negative BM.

21 Consider Triplet Maintenance For patients with a truly high-risk disease (eg, stage III myeloma with high-risk cytogenetics).

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23 Abbreviations

24 Abbreviations (cont)

25 References

26 References (cont)

27 References (cont)


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