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Mechanisms of Loss of Heterozygosity in Neurofibromatosis Type 1-Associated Plexiform Neurofibromas
Katharina Steinmann, Lan Kluwe, Reinhard E. Friedrich, Victor-Felix Mautner, David N. Cooper, Hildegard Kehrer-Sawatzki Journal of Investigative Dermatology Volume 129, Issue 3, Pages (March 2009) DOI: /jid Copyright © 2009 The Society for Investigative Dermatology, Inc Terms and Conditions
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Figure 1 LOH analysis in 13 plexiform neurofibromas. Tumor acronyms are indicated above. In those seven tumors highlighted with gray rectangles, LOH was caused by a deletion according to MLPA. The markers located in the NF1 microdeletion interval are underlined. Black circles: LOH, white circle: no LOH, striped circles: marker not informative, and gray filled circle: not determined. Journal of Investigative Dermatology , DOI: ( /jid ) Copyright © 2009 The Society for Investigative Dermatology, Inc Terms and Conditions
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