1. Both NE and BMI microinjection induce CRF gene transcription in the parvocellular division of the PVH.Left, Dark-field photomicrographs depicting CRF hnRNA expression in the parvocellular division of the PVH after microinjection of saline (Sal), 100 pmol of...
Both NE and BMI microinjection induce CRF gene transcription in the parvocellular division of the PVH.Left, Dark-field photomicrographs depicting CRF hnRNA expression in the parvocellular division of the PVH after microinjection of saline (Sal), 100 pmol of BMI, and 25 nmol of NE. Animals were killed 20 min after microinjection. Both NE and BMI microinjection produce a robust increase in hnRNA encoding for CRH peptide in the parvocellular division of the PVH. Magnification: 45×. Right, Mean ± SEM relative levels of CRF hnRNA in the parvocellular PVH of rats killed 20 min after saline, NE, or BMI injection. n = 4–6 per group. *p < 0.05 by one-way ANOVA.
Rebecca L. Cole, and Paul E. Sawchenko J. Neurosci. 2002;22:
©2002 by Society for Neuroscience