1. Elimination of dendritic spines per 2 d.
Elimination of dendritic spines per 2 d. A, B, Example of a time-lapse series of images of a dendrite in WT (A) and KO (B) mice at an interval of 2 d. Arrowheads indicate eliminated spines. Scale bar, 2 μm. C, The elimination rates of dendritic spines per 2 d. Solid bars represent measurement data. Error bars represent SEM values from 6 and 12 dendrites for WT and Fmr1 KO mice, respectively. KO mice seemed to have a higher elimination rate, although the difference was not significant (Mann–Whitney U test, U = 17, p = 0.08b). Hatched bars represent elimination rates calculated from the model shown with the dashed lines (Fig. 3E,F; Eqs. 6–8). Error bars represent 95% confidence intervals.
Kazuhiko Ishii et al. eNeuro 2018;5:ENEURO
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