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Reduction in craving expressed as area under the curve during 60 min for a) Nicorette 4 mg gum (♦), mouth spray (▴), lozenge (•) and placebo lozenge (▪); and b) Nicorette 4 mg gum (⋄), pouch (▵) and placebo pouch (□) [20]. Reduction in craving expressed as area under the curve during 60 min for a) Nicorette 4 mg gum (♦), mouth spray (▴), lozenge (•) and placebo lozenge (▪); and b) Nicorette 4 mg gum (⋄), pouch (▵) and placebo pouch (□) [20]. VAS: visual analogue scale. K. O. Fagerström, and C. A. Jiménez-Ruiz Eur Respir Rev 2008;17: ©2008 by European Respiratory Society
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