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Published byAnnika Leppänen Modified over 5 years ago
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Mammary stem cells and progenitors: targeting the roots of breast cancer for prevention
(A) Schematic of the human breast highlighting terminal ductal lobular units (TDLUs), the site of origin in a number of breast cancers. (B) Some of the major risk factors underlying high‐risk status for breast cancer. (C) Schematic of a ductal cross‐section, depicting the progression of breast cancer from normal bi‐layered epithelium to hyperplasia, to hyperplasia with atypia, to ductal carcinoma in situ, and finally to invasive disease. IF THIS IMAGE HAS BEEN PROVIDED BY OR IS OWNED BY A THIRD PARTY, AS INDICATED IN THE CAPTION LINE, THEN FURTHER PERMISSION MAY BE NEEDED BEFORE ANY FURTHER USE. PLEASE CONTACT WILEY'S PERMISSIONS DEPARTMENT ON OR USE THE RIGHTSLINK SERVICE BY CLICKING ON THE 'REQUEST PERMISSIONS' LINK ACCOMPANYING THIS ARTICLE. WILEY OR AUTHOR OWNED IMAGES MAY BE USED FOR NON-COMMERCIAL PURPOSES, SUBJECT TO PROPER CITATION OF THE ARTICLE, AUTHOR, AND PUBLISHER. EMBO J, Volume: 38, Issue: 14, First published: 21 June 2019, DOI: ( /embj )
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