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The HIV-Associated Enteric Microbiome Has Gone Viral

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Presentation on theme: "The HIV-Associated Enteric Microbiome Has Gone Viral"— Presentation transcript:

1 The HIV-Associated Enteric Microbiome Has Gone Viral
Brent E. Palmer, Sam X. Li, Catherine A. Lozupone  Cell Host & Microbe  Volume 19, Issue 3, Pages (March 2016) DOI: /j.chom Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 Expansion of the Enteric Virome Contributes to HIV/SIV Disease Progression HIV infection leads to massive depletion of CD4+ T cells in the gut-associated lymphoid tissue (GALT) and is associated with gastrointestinal (GI) damage and disease. The current studies show that severe immunodeficiency caused by HIV/SIV infection is linked with expansion of the viral component of the gut microbiome. Enteric viruses may contribute to further GI damage and HIV/SIV disease progression by direct infection of cells along the GI tract. Cell Host & Microbe  , DOI: ( /j.chom ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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