1. TLRs of Our Fathers Immunity
Mihai G. Netea, Leo A.B. Joosten 
Immunity 
Volume 44, Issue 2, Pages (February 2016)
DOI: /j.immuni
Copyright © 2016 Elsevier Inc. Terms and Conditions

2. Figure 1 Introgression from Archaic Humans in Innate Immune Genes
Introgression of ancient DNA from our hominin cousins caused up to 4%–6% of the DNA of modern humans from Asia and Europe to be of Neandertal or Denisovan origin. Genes of the innate immune system, such as the TLR cluster, are more heavily influenced by introgression. The admixture of Neandertal and Denisovan haplotypes in the modern genome of the Eurasians, but not Africans, might partly explain differences in susceptibility to immune-mediated diseases.
Immunity  , DOI: ( /j.immuni )
Copyright © 2016 Elsevier Inc. Terms and Conditions