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Coinjection of CAFs induces a collagen cross-link switch in tumor stroma. Coinjection of CAFs induces a collagen cross-link switch in tumor stroma. A,

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Presentation on theme: "Coinjection of CAFs induces a collagen cross-link switch in tumor stroma. Coinjection of CAFs induces a collagen cross-link switch in tumor stroma. A,"— Presentation transcript:

1 Coinjection of CAFs induces a collagen cross-link switch in tumor stroma.
Coinjection of CAFs induces a collagen cross-link switch in tumor stroma. A, quantification of collagen content (left) and total collagen cross-links (right; mol/mol of collagen) in tumors generated by subcutaneous injection of 344SQ cells alone (344SQ) or in combination with CAFs (344SQ+CAF). B–D, tumors subjected to quantification of an LCC (HHMD; B), HLCCs (DHLNL and Pyridinoline; C), and HLNL (D). Total cross-links in A were sum of cross-links in B–D. E, HLCC-to-LCC ratio determined from B and C. Daniela Pankova et al. Mol Cancer Res 2016;14: ©2016 by American Association for Cancer Research

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