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Fig. 1. Effects of Cancer Genetic Panel Testing on at-Risk Individuals Frost, Anja S.; Toaff, Miriam; Biagi, Tara; Stark, Elizabeth; McHenry, Allison; Kaltman, Rebecca Obstetrics & Gynecology131(6): , June 2018. doi: /AOG Schematic of genetic testing performed on study participants. *Patients with two mutations (n=4).Frost. Cancer Genetic Panel Testing in At-Risk Patients. Obstet Gynecol 2018. Copyright © 2019 by The American College of Obstetricians and Gynecologists
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Table 1. Effects of Cancer Genetic Panel Testing on at-Risk Individuals Frost, Anja S.; Toaff, Miriam; Biagi, Tara; Stark, Elizabeth; McHenry, Allison; Kaltman, Rebecca Obstetrics & Gynecology131(6): , June 2018. doi: /AOG Breakdown of Panel Tests Performed Copyright © 2019 by The American College of Obstetricians and Gynecologists
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Table 2. Effects of Cancer Genetic Panel Testing on at-Risk Individuals Frost, Anja S.; Toaff, Miriam; Biagi, Tara; Stark, Elizabeth; McHenry, Allison; Kaltman, Rebecca Obstetrics & Gynecology131(6): , June 2018. doi: /AOG Breakdown of Deleterious Mutations and Associated Cancer Risks Copyright © 2019 by The American College of Obstetricians and Gynecologists
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Fig. 2. Effects of Cancer Genetic Panel Testing on at-Risk Individuals Frost, Anja S.; Toaff, Miriam; Biagi, Tara; Stark, Elizabeth; McHenry, Allison; Kaltman, Rebecca Obstetrics & Gynecology131(6): , June 2018. doi: /AOG Summary of mutations among panel-tested individuals (n=65 patients, n=69 mutations). Percentages are based on total number of mutations, not number of individuals, because four individuals had two mutations.Frost. Cancer Genetic Panel Testing in At-Risk Patients. Obstet Gynecol 2018. Copyright © 2019 by The American College of Obstetricians and Gynecologists
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Fig. 3. Effects of Cancer Genetic Panel Testing on at-Risk Individuals Frost, Anja S.; Toaff, Miriam; Biagi, Tara; Stark, Elizabeth; McHenry, Allison; Kaltman, Rebecca Obstetrics & Gynecology131(6): , June 2018. doi: /AOG Clinical management recommendations after testing results. *Including breast, pelvic, and thyroid examinations. †Including mastectomy, salpingo-oophorectomy, hysterectomy, and colectomy. TVUS, transvaginal ultrasonography; REI, reproductive endocrinology; PSA, prostate-specific antigen; DRE, digital rectal examination; MRI, magnetic resonance imaging.Frost. Cancer Genetic Panel Testing in At-Risk Patients. Obstet Gynecol 2018. Copyright © 2019 by The American College of Obstetricians and Gynecologists
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Fig. 4. Effects of Cancer Genetic Panel Testing on at-Risk Individuals Frost, Anja S.; Toaff, Miriam; Biagi, Tara; Stark, Elizabeth; McHenry, Allison; Kaltman, Rebecca Obstetrics & Gynecology131(6): , June 2018. doi: /AOG Distribution of variants of unknown significance.Frost. Cancer Genetic Panel Testing in At-Risk Patients. Obstet Gynecol 2018. Copyright © 2019 by The American College of Obstetricians and Gynecologists
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