1. Structure of the Xist gene.
Structure of the Xist gene. (a) The mouseXist gene and the human XIST gene comprise six and eight exons, respectively. (b) Schematic representation of theXist RNA. The mouse Xist RNA is 15 kb long, and the human XIST RNA is 17 kb long. Corresponding conserved repetitive sequences in exons 1 (regions A, B, C, and D) and 6 (region E) are indicated by similarly hatched regions. The numbers of repeats are different between the mouse and human. (c) Nucleotide positions of the repetitive sequences are shown. Data are from references18 and 21.
Tetsuya Goto, and Marilyn Monk Microbiol. Mol. Biol. Rev. 1998; doi: