Presentation is loading. Please wait.

Presentation is loading. Please wait.

Anastrozole single-dose protocol in women with oligo- or anovulatory infertility: results of a randomized phase II dose–response study  Donald Tredway,

Similar presentations


Presentation on theme: "Anastrozole single-dose protocol in women with oligo- or anovulatory infertility: results of a randomized phase II dose–response study  Donald Tredway,"— Presentation transcript:

1 Anastrozole single-dose protocol in women with oligo- or anovulatory infertility: results of a randomized phase II dose–response study  Donald Tredway, M.D., Ph.D., Joan C. Schertz, M.Sc., Daena Bock, M.S., George Hemsey, M.B.A., Michael P. Diamond, M.D.  Fertility and Sterility  Volume 95, Issue 5, Pages e8 (April 2011) DOI: /j.fertnstert Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Follicular development (mean number of follicles >11 mm in diameter) for all patients who ovulated in any cycle. The LH surge appears separately because the timing of its occurrence is variable. AST = anastrozole; CC = clomiphene citrate. Fertility and Sterility  , e8DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

3 Serum levels of anastrozole (AST) and clomiphene citrate (CC) in cycle 1 of patients in the pharmacokinetic subgroup. The LH surge appears separately because the timing of its occurrence is variable. Fertility and Sterility  , e8DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

4 Median percentage change in E2 in cycle 1 in patients in the pharmacodynamic subgroup who ovulated. The LH surge appears separately because the timing of its occurrence is variable. AST = anastrozole; CC = clomiphene citrate. Fertility and Sterility  , e8DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

5 Median percentage change of T from before dose to day 12 in patients who ovulated. AST = anastrozole; CC = clomiphene citrate. Fertility and Sterility  , e8DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

6 Median percentage change of androstenedione from before dose to day 12 in patients who ovulated. AST = anastrozole; CC = clomiphene citrate. Fertility and Sterility  , e8DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions


Download ppt "Anastrozole single-dose protocol in women with oligo- or anovulatory infertility: results of a randomized phase II dose–response study  Donald Tredway,"

Similar presentations


Ads by Google