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SIR data for all CZP-treated patients (RCT+OLE) for each malignancy type, standardised to the general population by age and gender (GLOBOCAN and SEER).

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Presentation on theme: "SIR data for all CZP-treated patients (RCT+OLE) for each malignancy type, standardised to the general population by age and gender (GLOBOCAN and SEER)."— Presentation transcript:

1 SIR data for all CZP-treated patients (RCT+OLE) for each malignancy type, standardised to the general population by age and gender (GLOBOCAN and SEER). SIR data for all CZP-treated patients (RCT+OLE) for each malignancy type, standardised to the general population by age and gender (GLOBOCAN and SEER). (A) All malignancies excluding NMSC (GLOBOCAN data). (B) Lymphatic and haematopoietic malignancies (GLOBOCAN data). (C) All malignancies excluding NMSC (SEER data). *There were no lymphatic or haematopoietic malignancies in the axSpA subpopulation. Forest plots show SIRs with 95% CIs. PY calculated using total years of CZP exposure from the first dose of CZP to end of AE exposure period (if no malignancy) or to first malignancy. AE, adverse event; axSpA, axial spondyloarthritis; CD, Crohn’s disease; CZP, certolizumab pegol; NA, not applicable; NMSC, non-melanoma skin cancer; OLE, open-label extensions; PsA, psoriatic arthritis; PSO, psoriasis; PY: patient-years; RA, rheumatoid arthritis; RCT, randomised controlled trials; SIR, standardised incidence ratio. Jeffrey R Curtis et al. RMD Open 2019;5:e000942 Copyright © BMJ Publishing Group & EULAR. All rights reserved.

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